Recent highlights

2013

PAPER! Alexandra's paper PINT – a software for integration of peak volumes and extraction of relaxation rates is now accepted for publication. Congratulations Alexandra!

 

500 MHz SPECTROMETER FINALLY INSTALLED!

 

 

 

 

 

 

2012

FUNDING! Patrik was granted funding from the Swedish research council.

 

PAPERS! The first papers featuring only group members are now out! First one: P. Lundström*, A. Ahlner and A.T. Blissing (2012) Isotope labeling methods for relaxation measurements. In Isotope Labeling methods for Biomolecular NMR. (ed. H.S. Atreya). Second one: P. Lundström*, A. Ahlner and A.T. Blissing (2012) Isotope labeling methods for large systems. In In Isotope Labeling methods for Biomolecular NMR. (ed. H.S. Atreya)

 

TALKS! Alexandra gave a lecture entitled "NMR Spectroscopy Results Confirm the Importance of a Regulatory and  a Catalytic Spine in the Kinase Domain of Ephrin type-B Receptor 2" at the 7th Protein Kinases in Drug Discovery conference in Boston, MA. She also gave a lecture at the 16th Annual Conference of the Swedish Structural Biology Network, Tällberg, Sweden, ith the title "Biophysical characterization of the kinase domain of EphB2 by NMR spectroscopy".

 

PAPER! P. Neudecker, P. Robustelli, A. Cavalli, P. Walsh, Patrik Lundström, A. Zarrine-Afsar, Simon Sharpe, M. Vendruscolo, L.E. Kay (2012) Structure of an Intermediate State in Protein Folding and Aggregation. Science 336(6079):362-366.

 

PAPER! A. Bach, B.H. Clausen, M. Møller, B. Vestergaard, C.N. Chi, A. Round, P.L. Sørensen, K.B., Nissen, J.S. Kastrup, M. Gajhede, P. Jemth, A.S. Kristensen, Patrik Lundström, K.L. Lambertsen and K. Strømgaard. (2012) High-affinity dimeric inhibitor of PSD-95 protects against ischemic brain damage. Proc. Natl. Acad. Sci. U.S.A 109(9):3317-3322.

 

500 MHz SPECTROMETER has arrived and is pending installation!

 

 

 

 

 

 

 

 

 

 

 

500 MHz magnet

 

 

PAPER! A.L. Hansen, Patrik Lundström, A. Velyvis and L.E. Kay (2012) Quantifying millisecond exchange dynamics in proteins by CPMG relaxation dispersion NMR using side-chain 1H probes. J. Am. Chem. Soc. 134(6):3178-3189

 

PAPER! S. R. Haq, C. N. Chi, A. Bach, J. Dogan, Å. Engström, G. Hultqvist, A. Karlsson, Patrik Lundström, L. C. Montemiglio, K. Strømgaard, S. Gianni and P. Jemth. Side chain interactions form late and cooperatively in the binding reaction between disordered peptide and PDZ domain. (2012) J. Am. Chem. Soc. 134(1):599-605.

 

 

2011

FUNDING! Patrik and Olle Stål at Linköping University have jointly been awarded a seeding grant from the LiU Cancer Network.

 

GIFT! Thanks to a collaboration with Medivir AB we have been granted their 500 MHz NMR spectrometer.

 

AWARD! Alexandra got an award for best poster at the European Protein Society meeting in Stockholm.

 

PAPER! C.N. Chi, A. Bach, K. Strømggard, Patrik Lundström, N. Ferguson and P. Jemth. Biophysical characterization of the complex between human papillomavirus E6 and SAP97. (2011) J. Biol. Chem. 286:3597-3606.

 

 

2010

NEW EQUIPMENT! The department has purchased and installed a brand new Varian 14.1 T magnet to be used with our Inova console.

 

 

 

 

 

 

 

 

 

600 MHz NMR spectrometer

 

PAPER! H. Ghasriani, T. Ducat, C.T. Hart, F. Hafizi, N. Chang, A. Al-Baldawi, S.H. Ayed, Patrik Lundström, J.R. Dillon and N.K. Goto. (2010) Appropriation of the MinD protein-interaction motif by the dimeric interface of the bacterial cell division regulator MinE. Proc. Natl. Acad. Sci. USA 107(43):18416-18421.

 

 

2009

REVIEW! Patrik Lundström, P. Vallurupalli, D.F. Hansen and L.E. Kay. Isotope labeling methods for studies of excited protein states by relaxation dispersion NMR spectroscopy. (2009) Nat. Protoc. 4(11):1641-1648.

 

PAPER! R. Auer , P. Neudecker, D.R. Muhandiram, Patrik Lundström, D.F. Hansen, R. Konrat and L.E. Kay. Measuring the signs of 1Ha chemical shift differences between ground and excited protein states by off-resonance spin-lock R1rho NMR Spectroscopy. (2009) J. Am. Chem. Soc. 131(31):10832-10833.

 

PAPER! Patrik Lundström, H. Lin and L.E. Kay. Measuring 13Cb chemical shifts of excited states in proteins by relaxation dispersion NMR spectroscopy. (2009) J. Biomol NMR 44(3):139-155.

 

 

 

Page responsible: patrik.lundstrom@liu.se
Last updated: Fri May 10 14:42:54 CEST 2013