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Publications

Articles

1. Kågedal K., Bironaité D., Öllinger K. (1999) Anthraquinone cytotoxicity and apoptosis in primary cultures of rat hepatocytes. Free Rad. Res. 31, 419-428.
2. Kågedal K, Zhao M, Svensson I, Brunk UT. (2001) Sphingosine-induced apoptosis is dependent on lysosomal proteases. (2001) Biochemical Journal 359: 335-343
3. Kågedal K., Johansson U., Öllinger K (2001) The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress. FASEB J Exp 10.1096/fj.00-0708fje
4. Roberg K, Kågedal K, Öllinger K (2002) Microinjection of Cathepsin D induces caspase dependent apoptosis in fibroblasts. Am. J. Pathol. 161, 89-96
5. Terman A, Neuzil J, Kågedal K, Öllinger K, Brunk UT. (2002) Decreased apoptotic response of inclusion-cell disease fibroblasts: A consequence of lysosomal enzyme missorting? Exp. Cell Res. 274, 9-15.
6. Nilsson C, Kågedal K, Johansson U, Öllinger K, Analysis of cytosolic and lysosomal pH in apoptotic cells using flow cytometry. (2003) Methods in Cell Science 25, 185-194
7. Quinn C, Kågedal K, Terman A, Stroikin J, Brunk UT, Jessup W, Garner B. Induction of fibroblast apolipoprotein-E expression during apoptosis, starvation-induced growth arrest and mitosis (2004) J. Biol. Chem. 378, 753-761
8. Kågedal K, Johansson AC, Johansson U, Heimlich G, Roberg K, Wang N, Jürgensmeier N and Öllinger K. Lysosomal membrane permeabilization during apoptosis – involvement of Bax? (2005) 86 (5):309-321 Int. J. Exp. Pathol.
9. Bivik C. Larsson, P. Kågedal, K. Rosdahl, I. Öllinger, K. (2005) UVA/B induced apoptosis in human melanocytes involves translocation of cathepsins and Bcl-2 family members. (2006) J Invest Derm 126 (5): 1119-1127
10. Nilsson C, Johansson U, Johansson AC, Kågedal K and Öllinger K. Cytosolic acidification and lysosomal alkalinisation during TNF- induced apoptosis in U937 cells. (2006) Apoptosis 11(7): 1149-1159
11. Sörgjerd K, Klingstedt T, Lindgren M, Kågedal K, Hammarström P. Prefibrillar transthyretin oligomers and cold stored native tetrameric transthyretin are cytotoxic in cell culture. (2008) Biochem Biophys Res Commun. 377(4):1072-8
12. Zheng L, Kågedal K (shared first two authors), Dehvari N, Benedikz E, Cowburn R, Marcusson J, Terman A. Oxidative stress induces macroautophagy of amyloid beta-protein and ensuing apoptosis. (2009) Free Radic Biol Med 46(3):422-9
13. Agholme L. Lindström T. Kågedal K, Marcusson J. Hallbeck M. A novel method to differentiate SH-SH5Y cells into cells with morphological and biochemical characteristics of mature neurons – An in vitro model for neuroscience. (2010) J Alzheimer’s Disease 2010;20(4):1069-82.
14. Kågedal K, Kim WS, Appelqvist H, Chan S, Agholme L, McCann H, Halliday G, and Garner B. Increased expression of the lysosomal cholesterol transporter Niemann-Pick C in Alzheimer’s disease. (2010) Biochim Biophys Acta 1801(8):831-8
15. Kim WS, Chan S, Bhatia S, Agholme L, Kågedal K, Hill A, McCann H, Halliday G, Mucke L, Garner B. Increased ATP-binding cassette transporter A1 expression in Alzheimer’s disease hippocampal neurons. (2010) J. Neuroscience 21(1):193-2
16. Appelqvist H, Nilsson C, Garner B, Brown A, Kågedal K, Öllinger K. Attenuation of the lysosomal death pathway by lysosomal cholesterol accumulation (2010) In press Am J Pathol

Reviews and book chapters

1. Neuzil J, Kågedal K, Andera L, Weber C, Brunk UT. (2001) Vitamin E analogs: A new class of multiple action agents with anti-neoplastic and anti-atherogenic activity. Apoptosis 7: 177-1852
2. Öllinger K, Kågedal K (2002) Induction of apoptosis by redox-cycling quinones. Subcell. Biochem., 36, 151-170
3. Johansson A-C, Appelqvist H, Nilsson C, Kågedal K, Roberg K, Öllinger K Regulation of apoptosis-associated lysosomal membrane permeabilization. (2010) Apoptosis 15(5):527-40


 


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Last updated: Fri Dec 03 16:59:27 CET 2010